ABSTRACT
Abstract INTRODUCTION: The recent circulation of arboviruses transmitted by vectors, such as dengue, chikungunya, and Zika, is concerning due to the high morbidity rates, clinical complications, and increased demand on health services. The objective of this study was to analyze the clinical and epidemiological aspects of an epidemic caused by arboviruses in the municipality of Santa Luzia, Minas Gerais, Brazil. METHODS: Longitudinal study of patients with acute febrile disease and suspected arbovirus infection reported to Brazilian Notifiable Disease Information System (Sistema de Informação de Agravos de Notificação) from the epidemiological week 44 of 2015 to epidemiological week 52 of 2016. Patients with confirmed chikungunya were followed-up for 18 months and those with Zika for 15 months. Additionally, we analyzed and described the temporal distribution of confirmed cases of these arboviruses in this municipality. RESULTS: Overall 3,531 arboviruses cases, including 3,481 (98.7%) cases of dengue, 38 (1.0%) cases of chikungunya, and 12 (0.3%) cases of Zika were confirmed. The highest incidence of arbovirus infection occurred in the first quarter of 2016 (epidemiological week 7 to 14). The most frequent symptoms were for dengue, which included fever, headache, retro-orbital pain, and exanthema. Chikungunya infection was associated with fever, myalgia, arthralgia, and rash while Zika infection with pruritus and rash. CONCLUSIONS: Given the similarities in the initial clinical profiles of these arboviruses, it is important to perform a detailed clinical analysis, laboratory diagnosis, and patient follow-up.
Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adolescent , Adult , Aged , Dengue/epidemiology , Chikungunya Fever/epidemiology , Zika Virus Infection/epidemiology , Brazil/epidemiology , Incidence , Longitudinal Studies , Disease Notification , Endemic Diseases , Middle AgedABSTRACT
Objetivo: determinar la prevalencia del síndrome de sobrecarga del cuidador primario del adulto mayor, y los factores asociados, en una muestra de derechohabientes usuarios del Instituto Mexicano del Seguro Social (IMSS), Cárdenas, Tabasco. Materiales y métodos: diseño transversal, analítico. Universo: cuidadores primarios de adultos mayores derechohabientes usuarios del IMSS, numero fi nito e indeterminado. Muestra: no probabilística ajustada por conveniencia. Criterios de inclusión: edad mayor o igual a 18 años, cualquier sexo, sin enfermedades cognitivas ni discapacidades físicas que acudieron acompañando a su adulto mayor a recibir atención en unidades del IMSS durante Enero-Mayo de 2008, aceptaron participar y firmaron consentimiento informado. Variables: sociodemográficas, económicas, percepción de la funcionalidad familiar, síndrome de sobrecarga del cuidador. Instrumentos: Apgar Familiar, Escala de Zarit & Zarit. Análisis: estadística descriptiva, razón de posibilidades (OR) con 95% de confianza (p≤0,05). Software: SPSSR versión 10,0. Resultados: 100 cuidadores, 69% femeninos, 31% masculinos. Edad media 40,2 + 12,8 años, mínima 18, máxima 75. Prevalencia de síndrome de sobrecarga 15 % cuidadores. Factores asociados: estado civil no unido OR 24,89 (IC 95 7,92, 78,18), escolaridad baja OR 30,96 (IC 95 10,27, 93,33), disfunción familiar OR 9,08 (IC95 2,36, 34,90), estado civil unido OR 0,04 (IC 95 0,01, 0,13), escolaridad media-alta OR 0,03 (IC95 0,01, 0,10), familia funcional OR 0,11 (IC 95 0,03, 0,42). Conclusiones: la prevalencia del síndrome es baja, comparada con reportes similares, mientras que los factores asociados concuerdan con lo reportado por otros autores. Se requieren estudios más amplios para mejores conclusiones...
Objective: to determine overcharge syndrome in primary caretaker of elderly population prevalence, and associated factors, in a sample of Instituto Mexicano del Seguro Social (IMSS) users, Cardenas, Tabasco. Material and methods: cross-sectional and analytic design. Universe: primary caretakers of elderly population IMSS users, finite and indeterminate number. Sample: no randomized adjusted for convenience. Inclusion criterions: age ≥18 years, any gender, without cognitive diseases neither physic disabilities that goes accompanying elderly population to receive attention in IMSS units during January-May 2008, accept participate and signed informed consent. Variables: sociodemographics, economics, family functionality perception, caretaker overcharge syndrome. Instruments: Family Apgar, Zarit & Zarit Scale. Analysis: descriptive statistic, odds ratio (OR) with 95% of confidence (p≤0,05). Software: SPSSR version 10,0. Results: 100 caretakers, 69% females, 31 males. Mean age 40,2 +12,8 years, minimum 18, maximum 75. Overcharge syndrome prevalence 15 X 100 caretakers. Associated factors: single civil status OR 24,89 (CI 95 7,92, 78,18), low scholar lever OR 30,96 (CI 95 10,27, 93,33), family dysfunction OR 9,08 (CI 95 2,36, 34,90), united civil status OR 0,04 (CI 95 0,01, 0,13), medium-high scholar level OR 0,03 (CI95 0,01, 0,10), functional family OR 0,11 (CI95 0,03, 0,42). Conclusions: the syndrome prevalence is lower compared with similar reports, while that the associated factors according with the reported for other authors. Wider studies are required for better conclusions...
Subject(s)
Aged , Caregivers , FamilyABSTRACT
Se presenta el caso de una paciente que muestra algunas de las alteraciones fenotipicas principales de la monosomia 1q4 (epicanto, micrognatia, microcefalia) y en la cual el estudio citogenético mediante la técnica de bandas G permitió datectar, en todas las metafases, una translocación 1:14, cuyo punto de ruptura en el cromosoma 1 coincide con los reportados para la delección que origina la monosomia